Category: Science
MRA's Acral Melanoma Cell Line Catalog: A Launching Pad for Research
By Raj Talukdar, MRA Science Intern | 25 May 2021 In Science
In a collaborative effort to facilitate research focused on acral melanoma, MRA has created and annotated a catalog of acral melanoma cell lines from various institutions worldwide. The catalog includes cell lines created by researchers at Memorial Sloan Kettering Cancer Center, Wistar Institute, Yale University, the University of Zurich, the Queensland Institute of Medical Research in Australia and more.
Firming the Foundation: Pathology, Rare Melanomas, and Moving the Field Forward
By Cody Barnett, MPH, MRA Senior Director of Communications & Patient Engagement | 21 May 2021 In Science, Treatment
When Dr. Priyadharsini Nagarajan talks about her work at MD Anderson Cancer Center, her energy and excitement could light up any room. That’s because Dr. Nagarajan – a pathologist who specializes in skin (called a ‘dermatopathologist’) – sees her work as critical to creating a firm foundation for all subsequent...
Melanoma Research Alliance Announces $8.1 million in Research Awards
By Cody Barnett, MPH, MRA Senior Director of Communications & Patient Engagement | 27 April 2021 In News, Prevention, Science, Treatment
The Melanoma Research Alliance, the largest non-profit funder of melanoma research, is proud to announce $8.1 million in funding for 34 new research awards. The awards, issued on the cusp of Melanoma Awareness Month, provide critical funding to address urgent unmet needs in melanoma.
A New Treatment Approach in the Arsenal: Neoadjuvent Therapy
23 April 2021 In Allies & Partnerships, News, Science, Treatment
Surgery is the backbone of melanoma treatment and is curative for the vast majority of patients with localized melanoma. However, even if surgery successfully removes all detectible traces of tumor tissue, some patients will still experience a melanoma relapse. Can neoadjuvant therapy, an experimental approach, reduce the risk of recurrence?
UV Exposure & Risk of Cutaneous Melanoma in Skin of Color
By Rachel Fischer, Ph.D., Associate Director, Scientific Program & Registry | 14 April 2021 In News, Prevention, Science
In JAMA Dermatology, a team led by Adewole S. Adamson, MD, from The University of Texas at Austin, investigates whether there is an association, specifically in People of Color, between UV exposure and melanoma. MRA breaks down what this research means and how it should impact your sun safety practices.
Dr. James Allison on the Path to More Effective Immunotherapies
24 March 2021 In Science, Treatment
When MRA co-founder and Board Chair Debra Black introduced James Allison of the University of Texas MD Anderson Cancer Center at MRA’s 2020 Scientific Retreat, she described him as the man “who changed the way cancer patients are treated forever.” This fitting introduction is due to Allison’s pioneering work to mainstream the...
Relentless in the Fight: Dr. F. Stephen Hodi
5 March 2021 In Melanoma Stories, Science
Every revolution needs trailblazers—people who restlessly and relentlessly search for paths forward. At MRA, we’re fortunate to partner with innovative trailblazers who are guiding the entire field of melanoma further, such as two time MRA-funded investigator Dr. F. Stephen Hodi.
Estimating Melanoma Risk by Examining Skin’s Mutational Burden
By Cody Barnett, MPH, MRA Senior Director of Communications & Patient Engagement | 10 February 2021 In Prevention, Science
We’ve known for decades that most melanomas – formed from the color-producing cells in our skin called melanocytes – are predominantly caused by UV-radiation-induced damage from the sun or indoor tanning devices. This damage is cumulative but is often invisible.
Melanoma Models for the Next Decade of Progress
By Kristen Mueller, PhD | 8 February 2021 In Science
Despite the tremendous progress that’s been made over the past decade for patients with melanoma, nearly half of patients do not benefit from currently approved therapies. Developing novel therapies for these individuals is a daunting challenge that begins with laboratory studies and hopefully ends with a drug candidate that is...
Personalized Vaccines for Melanoma – An Update
By Marc Hurlbert, PhD, MRA Chief Executive Officer | 2 February 2021 In Science, Treatment
Vaccines work by priming the immune system, thereby reducing the severity and duration of symptoms or lowering the risk of becoming infected at all. And while vaccines have changed the world for infectious disease, did you know they can also help combat cancers.