Category: Treatment


Approaches to Neoadjuvant Treatment in Melanoma: A Public Workshop Organized by the FDA and MRA

13 November 2019 In Events, Science, Treatment

On November 6, 2019, the FDA and the Melanoma Research Alliance co-hosted a public workshop to identify, discuss, and address key issues, challenges and opportunities in the pursuit of neoadjuvant therapies for patients with surgically resectable melanoma. This exciting, half-day workshop brought together clinicians, researchers, regulators, and patient advocates to explore opportunities and discuss challenges in the development of neoadjuvant therapies for melanoma. The workshop took place at National Harbor (outside of Washington, D.C.) with opportunities to participate in person and via simultaneous webcast.

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Bob Enrolls in Clinical Trial Testing NeoAdjuvant Therapy for Melanoma

By Cody R. Barnett, MRA Director of Communications | 2 November 2019 In Melanoma Stories, Science, Treatment

After being diagnosed with Stage 3 melanoma, Bob chose to enroll in a clinical trial at Georgetown University, comparing the effectiveness of treating melanoma with pembrolizumab before or after surgery, what doctors call neo-adjuvant and adjuvant therapy respectively.

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MRA is Raising the Treatment Bar

31 October 2019 In Allies & Partnerships, Melanoma Stories, Science, Treatment

We have made unprecedented progress that is transforming what it means to be diagnosed with melanoma. Today, we have more treatment options than ever before—in fact 12 new options have earned FDA approval since MRA's founding. But, it's still not enough.

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Take Control After a Melanoma Diagnosis

25 September 2019 In Melanoma Stories, Treatment

You are used to giving the marching orders to your own body, but when cancer steers it in the wrong direction, it can feel like you are no longer in control. Yet this is when it’s most important to take control, stressed melanoma physicians, patients, and advocates at the 2019...

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SPORE Grants: Putting Collaboration Front & Center

By Cody R. Barnett, MRA Director of Communications | 24 September 2019 In Allies & Partnerships, Science, Treatment

In medicine, sometimes the biggest and most game-changing advancements come from a single person – who through tireless work – arrives at a true ‘eureka’ moment. This ‘go it alone’ concept is not only reinforced through television and movies, it’s also bolstered in the way the medical community makes research...

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Treating Melanoma Patients Before Surgery

3 September 2019 In Allies & Partnerships, Science, Treatment

Over 90% of patients who have their tumors surgically removed will never see their tumors come back or spread to other sites, but is there a way to prevent recurrence in those patients that will eventually go on to relapse? One approach currently being tested in clinical trials, termed neoadjuvant therapy, is to treat early stage patients with targeted or immunotherapy before surgical removal of their tumor.

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Acral Melanoma & Adjuvant Therapy – One Patient’s Decision

By Cody R. Barnett, MRA Director of Communications | 23 July 2019 In Melanoma Stories, Treatment

When David was diagnosed with Stage 3 acral melanoma he faced a major decision. The surgery to remove it was successful - but should he move forward with adjuvant therapy to reduce the risk of it returning? Learn more about the benefits - and risks - of this approach and read what David decided.

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New Models for Testing Melanoma Drugs and Vaccines

15 July 2019 In Science, Treatment

Before experimental drugs and vaccines can ever be tested in people, they must first be studied in models of the disease. These models allow researchers to investigate scientific questions that they cannot answer using people due to unknown risks.

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Can We Combine Immunotherapy and Targeted Therapy for Better Results?

By Kristen Mueller, Ph.D., MRA Scientific Program Director | 25 June 2019 In Science, Treatment

Researchers are now considering how to build upon the success of immune-based and targeted therapies to help even more patients live longer, healthier lives. This month, several studies reported on efforts to combine PD-1 based immunotherapy with BRAF/MEKi targeted therapy to form the first ‘triple combos’ in melanoma.

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Resisting Resistance

14 June 2019 In Science, Treatment

For too many patients, the incredible responses they experience from targeted and immunotherapies don't last. Resistance is a real challenge. At the MRA 2019 Scientific Retreat, several researchers reported on research funded by MRA to identify new ways to combat drug resistance, including a number of strategies that are already being tested in the clinic.

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