Category: Science


Resisting Resistance

14 June 2019 In Science, Treatment

For too many patients, the incredible responses they experience from targeted and immunotherapies don't last. Resistance is a real challenge. At the MRA 2019 Scientific Retreat, several researchers reported on research funded by MRA to identify new ways to combat drug resistance, including a number of strategies that are already being tested in the clinic.

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Mohs Surgery for Melanoma In Situ – Where We Stand

10 June 2019 In Melanoma Stories, Science

While effective and time tested, Wide Local Excision can cause significant scarring and even loss of function when performed in delicate areas. For non-melanoma skin cancers, such as basal cell carcinomas and squamous cell carcinomas, an alternative ‘tissue-sparing’ procedure is frequently performed called Mohs Micrographic Surgery. Can Mohs Surgery be safely used in melanoma in situ?

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Fighting For Her Life with a Clinical trial

By Cody R. Barnett, MRA Director of Communications | 7 June 2019 In Melanoma Stories, Science, Treatment

Colleen Wittoesch was a regular volunteer at MD Anderson Cancer Center. She came to the hospital every week to help out and spend time with patients and families in the melanoma clinic for going on seven years. Little did she know that in 2016 she too would walk through the clinic doors as a patient.

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Highlights from the 2019 Scientific Retreat

30 May 2019 In Allies & Partnerships, Events, Melanoma Stories, News, Prevention, Science, Treatment

Over the course of three days, MRA convened over 300 people from across the melanoma research community: patients, doctors, researchers, industry, and government. Participants discussed everything from new treatment approaches such as RNA-based vaccines, strategies to fight back against treatment resistance, and hurdles to testing neo-adjuvant therapies in melanoma.

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Clinical Trials to Watch: Turning Cold Tumors Hot

By Kristen Mueller, Ph.D., MRA Scientific Program Director | 15 May 2019 In Science, Treatment

We know that the billions of bacteria that live in our bodies can impact the way we respond to immunotherapy, but can we harness this help more patients respond these life-saving drugs?

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Research is Hope: MRA Announces $8.2 Million for New Grant Awards to Advance Melanoma Research

By Cody R. Barnett, MRA Director of Communications | 30 April 2019 In News, Science

In advance of Melanoma Awareness Month, the Melanoma Research Alliance (MRA), the largest non-profit funder of melanoma research, today announced funding for 33 innovative research awards totaling $8.26 million.

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Melanoma Vaccines Show Promise

14 April 2019 In Science, Treatment

While immunotherapy has transformed way melanoma is treated, about half of patients still do not respond. Researchers are pursuing multiple strategies to understand why this happens and to develop strategies to jumpstart a response. One approach showing promise in early clinical trials, comes in the form of new personalized vaccines being developed by Ugur Sahin of Johannes Gutenberg-Universität Mainz and BioNTech.

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What’s Next for the Microbiome in Melanoma?

By Kristen Mueller, Ph.D., MRA Scientific Program Director | 11 April 2019 In Science, Treatment

We know that the billions of bacteria that live in our bodies can impact the way we respond to immunotherapy, but can we harness this help more patients respond these life-saving drugs?

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This Engineer is Building a ‘Better’ Biopsy

By Cody R. Barnett, MRA Director of Communications | 20 March 2019 In Science

Biopsies are an important tool to determine if a mole or other lesion is cancerous. For most patients, the occasional biopsy is no big deal. However for patients facing multiple abnormal or otherwise ‘suspicious’ spots in highly visible places the prospect can be daunting. Dr. Jesse Wilson, an MRA-funded investigator, is an engineer on a mission to build a better biopsy.

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Bronze Bodies and Black Lungs: Five Ways the Tanning and Tobacco Industries Use the Same Playbook

By Charles Brodine, MRA Intern | 17 March 2019 In Prevention, Science

Dr. Alan Blum has crusaded against the tobacco industry for 30 years and now he's taking aim at the tanning industry. According to Blum, both the tobacco and tanning industries exploit people in similar ways, by targeting youth, downplaying their own corporate responsibility, infiltrating pop-culture, and indeed, by becoming prolific icons.

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