MRA’s Young Investigator Program: Bringing New Talent & Novel Ideas for Research Forward
In February, at the Ninth Annual MRA Scientific Retreat, a Young Investigator Breakfast brought together scores of past and current MRA Young Investigators where I connected with one of MRA’s first young investigators, Dr. Timothy Bullock.
The Power of Combination Therapies: One Patient’s Road to Remission
By Pooja H. Rambhia, MD Candidate, Case Western Reserve University | 28 February 2017 In Science, Treatment
Metastatic melanoma can be a devastating diagnosis to receive. Just hearing the word cancer for most is terrifying. While the fear is understandable, today new targeted therapies and immunotherapies are delivering new hope for many.
Melanoma Immunotherapy and Precision Medicine — a Medical Student’s Perspective
By Pooja H. Rambhia, MD Candidate, Case Western Reserve University | 20 January 2017 In Science
Malignant melanoma research has provided the perfect opportunity to explore the intersection of immunotherapy and precision medicine, which has greatly transformed melanoma therapeutics in the last decade.
Parallels between Disease States
Six months ago I was offered the opportunity to serve as President & CEO of MRA and in July, I officially began. For the past 24 years, I’ve worked in the HIV field and am struck by the many parallels that exist between my past work and melanoma.
Understanding Immunotherapy Part 3: CTLA-4
Now that you’ve read our background on immunotherapy and learned about PD-1, it’s time to focus on another protein that plays a key role in cancer development, CTLA-4. What is CTLA-4? In addition to displaying PD-1 on the cell surface, T cells also display CTLA-4.
Research Q&A: Dr. Tim Bullock
21 March 2016 In Science
In the latest blog post, we chatted with the University of Virginia’s Tim Bullock, Ph.D., a tumor immunologist in the Pathology Department and MRA-funded investigator. Read on to learn what he has to say about melanoma research and prevention efforts.
Understanding Immunotherapy Part 2: PD-1
Now that we’ve provided a brief background on immunotherapy, it’s time to dive more deeply into the subject. In the second installment of this blog series, we’ll be examining PD-1, a protein that plays a crucial role in cancer’s ability to hide from our immune systems. What is PD-1? PD-1...
Researcher Q&A: Dr. John D’Orazio
7 January 2016 In Science
In the latest blog post, we chatted with the University of Kentucky’s John D’Orazio, M.D., Ph.D., a pediatric hematologist oncologist, and a 2015 MRA grant awardee. Read on to learn what he has to say about melanoma research and prevention efforts.