Category: Science


Melanoma Treatments: Breakthroughs for Multiple Cancers — for Real and Right Now

By Louise M. Perkins, Ph.D., MRA Chief Science Officer | 10 July 2017 In Science, Treatment

While 2014 and 2015 offered a whirlwind of good news related to new melanoma treatments from immune to targeted therapy, since then, it’s been a bit quieter in melanoma. Although there has been exceptional news in regard to other cancers. Why is that, and what are the latest breakthroughs?

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Melanoma Research Alliance and the American Cancer Society Forge Research Partnership to Maximize Immunotherapy Benefit to Patients

By Pamela Goldsmith, MRA Director of Communications | 10 July 2017 In Allies & Partnerships, Science

The Melanoma Research Alliance (MRA) and the American Cancer Society (ACS) are partnering to fund much-needed research aimed at decreasing rare, but serious, side effects associated with checkpoint inhibitors in hopes of increasing further cancer immunotherapy benefit to patients.

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Non-invasive Detection Modalities and Metastatic Risk Stratification for Melanoma: Where Are We Now?

By Pooja H. Rambhia, MD Candidate, Case Western Reserve University | 10 July 2017 In Prevention, Science, Treatment

While dermatologists have advocated for patient education about irregular skin lesions in order to catch melanomas earlier, dermatologists ultimately play the largest role in the detection and excision of abnormal skin lesions via skin biopsy. However, visual recognition and assessment of pigmented skin lesions is limited to the eye of the dermatologist, and can be challenging for even the most experienced clinicians.

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Strides and Obstacles in Melanoma Research Spotlight on Martin McMahon, PhD

By Pamela Goldsmith, MRA Director of Communications | 6 June 2017 In Science, Treatment

Like so many in the melanoma research field, Martin McMahon, PhD, Huntsman Cancer Institute’s senior director of pre-clinical translation and Professor at the University of Utah, entered the melanoma field by accident.

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Melanoma Clinical Oncology Research: Interview with Dr. Joshua Arbesman

By Pooja H. Rambhia, MD Candidate, Case Western Reserve University | 6 June 2017 In Science, Treatment

As a third year medical student, MD Candidate Pooja Rambhia had the privilege of conducting an elective research year under Dr. Joshua Arbesman’s mentorship at University Hospitals Cleveland Medical Center. Arbesman has a unique role in translational basic science research within the realm of familial melanoma.

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The Genetics of Melanoma Goes Deep

By Kristen Mueller, Ph.D., MRA Scientific Program Director | 6 June 2017 In News, Science, Treatment

Due to the rapid advancements in DNA sequencing technologies, our understanding of the underlying genetic causes of cancer has increased substantially in the past decade. In the case of melanoma, researchers have now characterized in great detail the genetic changes that occur within tumor cells in melanoma of the skin, leading to the FDA approval of drugs targeting mutations in BRAF and MEK.

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What Gut Bacteria Tell Us About Treating Melanoma and Other Cancers

By Pamela Goldsmith, MRA Director of Communications | 3 April 2017 In News, Science, Treatment

Despite success in the use of immunotherapy to treat cancer by harnessing the body’s immune system to fight it, a major difficulty continues to be the range of responses to treatment among patients. It’s why researchers are exploring why some cancer patients exhibit astounding results with little side effects while others receive no benefits to the treatment and/or experience severe side effects.

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Is a Clinical Trial Right for You?

By Cody R. Barnett, MRA Director of Communications | 11 December 2015 In Science, Treatment

Clinical trials are key to bringing new treatments to patients, as we have seen with melanoma. Are they right for you?

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Spotlight on MRA’s Ninth Annual Scientific Retreat

By Louise M. Perkins, Ph.D., MRA Chief Science Officer | 28 February 2017 In Allies & Partnerships, Events, Science

In mid-February, MRA held its premiere research event — the 9th Annual Scientific Retreat, in Washington, DC. A total of 297 individuals registered for the meeting representing a spectrum of key stakeholders in melanoma including academic investigators, pharmaceutical and biotech company representatives, melanoma advocates from various different non-profit organizations, donors and government officials.

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Melanoma Prevention: The Latest Advances & Future Directions

By Pamela Goldsmith, MRA Director of Communications | 28 February 2017 In Events, Policy, Prevention, Science

During my interview with Susan Swetter, MD, Professor of Dermatology,
Stanford University and VA Palo Alto, at the Melanoma Research Alliance Ninth Annual Scientific Retreat in Washington, DC, I inquired about the Panel Discussion she was part of titled: News from the field: What’s going well and what remains to be done?

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